Research Associate – Human‑First Drug Discovery
parallel-bio · Vienna
Stellenbeschreibung
About the role
Join Parallel Bio’s Vienna lab to advance human‑first drug discovery by generating and characterising patient‑derived iPSC lines and organoid models. You will work closely with a multidisciplinary team to ensure high‑quality cellular resources and robust assay read‑outs.
Key responsibilities
- Derive, quality‑control and biobank iPSC lines from donor blood, including colony picking, clonal expansion and cryopreservation.
- Maintain iPSC and primary cultures and differentiate them into immune organoids using in‑house protocols, iteratively optimizing conditions for longevity and functional performance.
- Design, validate and execute functional assays such as flow cytometry panels, (q)PCR, immunofluorescence, ELISA and Luminex, and prepare samples for bulk RNA‑seq, scRNA‑seq and whole‑exome sequencing.
- Document experiments in electronic lab notebooks, write SOPs, and share findings with US and local teams, mentoring junior researchers.
Required profile
- MSc in molecular biology, cell biology, immunology, bioengineering or related field.
- Experience with aseptic human pluripotent stem cell culture (iPSC or ESC) and at least one year of tissue‑culture work.
- Hands‑on experience with flow cytometry (panel design and analysis), (q)PCR and ELISA.
- Familiarity with organoid or 3D spheroid culture and basic immunology concepts is a strong plus.
Required skills
- iPSC culture and cryopreservation
- Organoid differentiation and 3D culture
- Flow cytometry panel design and data analysis
- (q)PCR and ELISA assay execution
- Luminex and immunofluorescence imaging
- NGS sample preparation (bulk RNA‑seq, scRNA‑seq, whole‑exome)
- Electronic lab notebook / laboratory information system usage
What we offer
- Base salary of at least €40,000 per year, commensurate with experience.
- Flexible work arrangements to support work‑life balance.
- Inclusive, equal‑opportunity workplace with diverse international team.
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